Visible-Light-Promoted Atom Transfer Radical Cyclization of Unactivated Alkyl Iodides

Yangyang Shen(Institut Català d'Investigació Química), Josep Cornellà(Institut Català d'Investigació Química), Francisco Juliá‐Hernández(Institut Català d'Investigació Química), Rubén Martı́n(Institució Catalana de Recerca i Estudis Avançats)
ACS Catalysis
December 7, 2016
Cited by 98Open Access
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Abstract

A visible-light-mediated atom transfer radical cyclization of unactivated alkyl iodides is described. This protocol operates under mild conditions and exhibits high chemoselectivity profile while avoiding parasitic hydrogen atom transfer pathways. Preliminary mechanistic studies challenge the perception that a canonical photoredox catalytic cycle is being operative.


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