The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

Jacqueline A. L. MacArthur(European Bioinformatics Institute), Emily Bowler-Barnett(European Bioinformatics Institute), María Cerezo(European Bioinformatics Institute), Laurent Gil(European Bioinformatics Institute), Peggy Hall(National Institutes of Health), Emma Hastings(European Bioinformatics Institute), Heather Junkins(National Institutes of Health), Aoife McMahon(European Bioinformatics Institute), Annalisa Milano(European Bioinformatics Institute), Joannella Morales(European Bioinformatics Institute), Zoë May Pendlington(European Bioinformatics Institute), Danielle Welter(European Bioinformatics Institute), Tony Burdett(European Bioinformatics Institute), Lucia A. Hindorff(National Institutes of Health), Paul Flicek(European Bioinformatics Institute), Fiona Cunningham(European Bioinformatics Institute), Helen Parkinson(European Bioinformatics Institute)
Nucleic Acids Research
November 2, 2016
10.1093/nar/gkw1133
Cited by 2,377Open Access
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Abstract

The NHGRI-EBI GWAS Catalog has provided data from published genome-wide association studies since 2008. In 2015, the database was redesigned and relocated to EMBL-EBI. The new infrastructure includes a new graphical user interface (www.ebi.ac.uk/gwas/), ontology supported search functionality and an improved curation interface. These developments have improved the data release frequency by increasing automation of curation and providing scaling improvements. The range of available Catalog data has also been extended with structured ancestry and recruitment information added for all studies. The infrastructure improvements also support scaling for larger arrays, exome and sequencing studies, allowing the Catalog to adapt to the needs of evolving study design, genotyping technologies and user needs in the future.

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