The Value of FDG PET/CT in Treatment Response Assessment, Follow-Up, and Surveillance of Lung Cancer
Sara Sheikhbahaei(Johns Hopkins University), Esther Mena(Johns Hopkins University), Anusha Yanamadala(Johns Hopkins University), Siddaling Reddy(Johns Hopkins University), Lilja B. Sólnes(Johns Hopkins University), Jason Wachsmann(The University of Texas Southwestern Medical Center), Rathan M. Subramaniam(The University of Texas Southwestern Medical Center)
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Abstract
OBJECTIVE: The purpose of this article is to summarize the evidence regarding the role of FDG PET/CT in treatment response assessment and surveillance of lung cancer and to provide suggested best practices. CONCLUSION: FDG PET/CT is a valuable imaging tool for assessing treatment response for patients with lung cancer, though evidence for its comparative effectiveness with chest CT is still evolving. FDG PET/CT is most useful when there is clinical suspicion or other evidence for disease recurrence or metastases. The sequencing, cost analysis, and comparative effectiveness of FDG PET/CT and conventional imaging modalities in the follow-up setting need to be investigated.
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