Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

Jianjun Gao; Lewis Z. Shi; Hao Zhao; Jianfeng Chen; Liangwen Xiong; Qiuming He; Tenghui Chen; Jason Roszik; Chantale Bernatchez; Scott E. Woodman; Pei-Ling Chen; Patrick Hwu; James P. Allison; P. Andrew Futreal; Jennifer A. Wargo; Padmanee Sharma

doi:10.1016/j.cell.2016.08.069

Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

Jianjun Gao(The University of Texas MD Anderson Cancer Center), Lewis Z. Shi(The University of Texas MD Anderson Cancer Center), Hao Zhao(The University of Texas MD Anderson Cancer Center), Jianfeng Chen(The University of Texas MD Anderson Cancer Center), Liangwen Xiong(The University of Texas MD Anderson Cancer Center), Qiuming He(The University of Texas MD Anderson Cancer Center), Tenghui Chen(The University of Texas MD Anderson Cancer Center), Jason Roszik(The University of Texas MD Anderson Cancer Center), Chantale Bernatchez(The University of Texas MD Anderson Cancer Center), Scott E. Woodman(The University of Texas MD Anderson Cancer Center), Pei-Ling Chen(The University of Texas MD Anderson Cancer Center), Patrick Hwu(The University of Texas MD Anderson Cancer Center), James P. Allison(The University of Texas MD Anderson Cancer Center), P. Andrew Futreal(The University of Texas MD Anderson Cancer Center), Jennifer A. Wargo(The University of Texas MD Anderson Cancer Center), Padmanee Sharma(The University of Texas MD Anderson Cancer Center)

Cell

September 22, 2016

10.1016/j.cell.2016.08.069

Cited by 1,295Open Access

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