Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

Quanyin Hu(University of North Carolina at Chapel Hill), Chenggen Qian(Ingenierie des Materiaux polymeres), Wujin Sun(University of North Carolina at Chapel Hill), Jinqiang Wang(University of North Carolina at Chapel Hill), Zhaowei Chen(North Carolina State University), Hunter N. Bomba(North Carolina State University), Hongliang Xin(Nanjing Medical University), Qun‐Dong Shen(Ingenierie des Materiaux polymeres), Zhen Gu(North Carolina State University)
Advanced Materials
September 14, 2016
Cited by 241Open Access
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Abstract

A platelet-membrane-coated biomimetic nanocarrier, which can sequentially target the bone microenvironment and myeloma cells to enhance the drug availability at the myeloma site and decrease off-target effects, is developed for inhibiting multiple myeloma growth and simultaneously eradicating thrombus complication. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.


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