Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation

Masaya Yamaguchi(St. Jude Children's Research Hospital), Ryan T. VanderLinden(St. Jude Children's Research Hospital), Florian Weissmann(Research Institute of Molecular Pathology), Renping Qiao(Research Institute of Molecular Pathology), Prakash Dube(Max Planck Institute for Biophysical Chemistry), Nicholas G. Brown(St. Jude Children's Research Hospital), David Haselbach(Max Planck Institute for Biophysical Chemistry), Wei Zhang(University of Toronto), Sachdev S. Sidhu(University of Toronto), Jan‐Michael Peters(Research Institute of Molecular Pathology), Holger Stark(Max Planck Institute for Biophysical Chemistry), Brenda A. Schulman(St. Jude Children's Research Hospital)
Molecular Cell
August 1, 2016
Cited by 162Open Access
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