Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

Satoshi Inoue; Wanda Y. Li; Alan Tseng; Isabel Beerman; Andrew Elia; Sean C. Bendall; François Lemonnier; Ken J. Kron; David W. Cescon; Zhenyue Hao; Evan Lind; Naoya Takayama; Aline Cristiane Planello; Shu Yi Shen; Alan H. Shih; Dana M. Larsen; Qinxi Li; Bryan E. Snow; Andrew Wakeham; Jillian Haight; Chiara Gorrini; C. Bassi; Kelsie L. Thu; Kiichi Murakami; Alisha R. Elford; Takeshi Ueda; Kimberly Straley; Katharine Yen; Gerry Melino; Luisa Cimmino; Iannis Aifantis; Ross L. Levine; Daniel D. De Carvalho; Mathieu Lupien; Derrick J. Rossi; Garry P. Nolan; Rob A. Cairns; Tak W. Mak

doi:10.1016/j.ccell.2016.05.018

Mutant IDH1 Downregulates ATM and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2

Satoshi Inoue(Ontario Institute for Cancer Research), Wanda Y. Li(Ontario Institute for Cancer Research), Alan Tseng(Ontario Institute for Cancer Research), Isabel Beerman(Boston Children's Hospital), Andrew Elia(Ontario Institute for Cancer Research), Sean C. Bendall(Stanford University), François Lemonnier(Ontario Institute for Cancer Research), Ken J. Kron(Ontario Institute for Cancer Research), David W. Cescon(Ontario Institute for Cancer Research), Zhenyue Hao(Ontario Institute for Cancer Research), Evan Lind(Ontario Institute for Cancer Research), Naoya Takayama(University Health Network), Aline Cristiane Planello(Ontario Institute for Cancer Research), Shu Yi Shen(Ontario Institute for Cancer Research), Alan H. Shih(Memorial Sloan Kettering Cancer Center), Dana M. Larsen, Qinxi Li(Ontario Institute for Cancer Research), Bryan E. Snow(Ontario Institute for Cancer Research), Andrew Wakeham(Ontario Institute for Cancer Research), Jillian Haight(Ontario Institute for Cancer Research), Chiara Gorrini(Ontario Institute for Cancer Research), C. Bassi(Ontario Institute for Cancer Research), Kelsie L. Thu(Ontario Institute for Cancer Research), Kiichi Murakami(Ontario Institute for Cancer Research), Alisha R. Elford(Ontario Institute for Cancer Research), Takeshi Ueda(Ontario Institute for Cancer Research), Kimberly Straley(Agios Pharmaceuticals (United States)), Katharine Yen(Agios Pharmaceuticals (United States)), Gerry Melino(University of Rome Tor Vergata), Luisa Cimmino(Howard Hughes Medical Institute), Iannis Aifantis(Howard Hughes Medical Institute), Ross L. Levine(Memorial Sloan Kettering Cancer Center), Daniel D. De Carvalho(Ontario Institute for Cancer Research), Mathieu Lupien(Ontario Institute for Cancer Research), Derrick J. Rossi(Boston Children's Hospital), Garry P. Nolan(Stanford University), Rob A. Cairns(Ontario Institute for Cancer Research), Tak W. Mak(Ontario Institute for Cancer Research)

Cancer Cell

July 16, 2016

10.1016/j.ccell.2016.05.018

Cited by 198Open Access

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