Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

Xia Li; Qian Zhang; Yuanyuan Ding; Yiqi Liu; Dezhi Zhao; Kai Zhao; Qicong Shen; Xingguang Liu; Xuhui Zhu; Nan Li; Zhongyi Cheng; Guoping Fan; Qingqing Wang; Xuetao Cao

doi:10.1038/ni.3464

Methyltransferase Dnmt3a upregulates HDAC9 to deacetylate the kinase TBK1 for activation of antiviral innate immunity

Xia Li(Chinese Academy of Medical Sciences & Peking Union Medical College), Qian Zhang(Second Military Medical University), Yuanyuan Ding(Zhejiang University), Yiqi Liu(Zhejiang University), Dezhi Zhao(Zhejiang University), Kai Zhao(Chinese Academy of Medical Sciences & Peking Union Medical College), Qicong Shen(Second Military Medical University), Xingguang Liu(Second Military Medical University), Xuhui Zhu(Second Military Medical University), Nan Li(Second Military Medical University), Zhongyi Cheng(Tongji University), Guoping Fan(University of California, Los Angeles), Qingqing Wang(Zhejiang University), Xuetao Cao(Second Military Medical University)

Nature Immunology

May 30, 2016

10.1038/ni.3464

Cited by 200Open Access

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