Hemolytic Anemia in Wilson's Disease

Abstract

JAUNDICE is a common presentation of Wilson's disease and may precede the neurologic features by many years.1 , 2 Infective hepatitis is often invoked as an explanation of the initial episode, and Wilson's disease is rarely considered at that time. Subsequently, neurologic symptoms may lead to a correct diagnosis when such features as jaundice and ascites are attributed, in retrospect, to the cirrhosis of Wilson's disease. After this initial episode no further features suggesting hepatic involvement may appear despite neurologic abnormalities of many years' duration. Furthermore, ascites, of grave prognostic significance in most forms of cirrhosis, is often an early feature in . . .