Risk Factors for Gastrointestinal Bleeding in Critically Ill Patients

Deborah J. Cook(Hamilton Health Sciences), Hugh D. Fuller(Hamilton Health Sciences), Gordon Guyatt(Hamilton Health Sciences), John C. Marshall(Canadian Institutes of Health Research), David Leasa(Canadian Institutes of Health Research), Richard Hall(Victoria General Hospital), Timothy Winton(Canadian Institutes of Health Research), Frank Rutledge(Victoria General Hospital), Thomas R.J. Todd, Peter Roy(Victoria General Hospital), Jacques Lacroix(Jewish Rehabilitation Hospital), Lauren E. Griffith(Hamilton Health Sciences), Andrew R. Willan(Hamilton Health Sciences)
New England Journal of Medicine
February 10, 1994
Cited by 1,021Open Access
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Abstract

The efficacy of prophylaxis against stress ulcers in preventing gastrointestinal bleeding in critically ill patients has led to its widespread use. The side effects and cost of prophylaxis, however, necessitate targeting preventive therapy to those patients most likely to benefit.


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