Genetically humanized pigs exclusively expressing human insulin are generated through custom endonuclease-mediated seamless engineering
Yi Yang(Chinese Academy of Sciences), Liangxue Lai(Jilin University), Degong Ruan(Chinese Academy of Sciences), Yong Fan(Third Affiliated Hospital of Guangzhou Medical University), Zhen Ouyang(Jiangsu University), Nana Fan(Yulin University), Zhaoming Liu(Chinese Academy of Sciences), Lei Bu(Shanghai Medical College of Fudan University), Xiaofang Sun(Third Affiliated Hospital of Guangzhou Medical University), Han Wu(Chinese Academy of Sciences), Yu Zhao(Chinese Academy of Sciences), Qin Jin(Chinese Academy of Medical Sciences & Peking Union Medical College), Kepin Wang(Guangzhou Institutes of Biomedicine and Health), Bentian Zhao(Chinese Academy of Sciences), Xiaoping Li(Shanxi University), Quanjun Zhang(Chinese Academy of Sciences), Qishuai Liu(Chinese Academy of Sciences)
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