Structure–Activity Relationships of Phosphoinositide 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Dual Inhibitors: Investigations of Various 6,5-Heterocycles to Improve Metabolic Stability
Markian M. Stec(Amgen (United States)), Mark H. Norman(Amgen (United States)), Raju Subramanian(Gilead Sciences (United States)), Nancy R. Zhang(University of the Arts), Kevin Yang(Revolution Medicines (United States)), Leeanne Zalameda(Amgen (United States)), Tisha San Miguel(Amgen (United States)), Erin L. Mullady(Amgen (United States)), Jian Jiang(Xuzhou Medical College), Shon K. Booker(Amgen (United States)), Ling Wang(Guizhou University), Hongyu Liao, Paul E. Hughes(Amgen (United States)), Sean Caenepeel(Amgen (United States)), Kristin L. Andrews(Amgen (United States)), John D. McCarter(Amgen (United States)), Daniel J. Freeman(Amgen (United States)), Nuria Tamayo(Amgen (United States))
Cited by 44
Related Papers
Integrin activation controls metastasis in human breast cancer
|Proceedings of the National Academy of Sciences|2001|580
Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization
|Drug Metabolism and Disposition|2002|346
Effects of Fibrates on Metabolism of Statins in Human Hepatocytes
|Drug Metabolism and Disposition|2002|325