Defective Glucose Transport across the Blood-Brain Barrier as a Cause of Persistent Hypoglycorrhachia, Seizures, and Developmental Delay

Darryl C. De Vivo(NewYork–Presbyterian Hospital), Rosario Rich Trifiletti(NewYork–Presbyterian Hospital), Ronald I. Jacobson(NewYork–Presbyterian Hospital), Gabriel M. Ronen(Janeway Children's Health and Rehabilitation Centre), Ramin A. Behmand(University Hospitals of Cleveland), Sami I. Harik(University Hospitals of Cleveland)
New England Journal of Medicine
September 5, 1991
Cited by 790Open Access
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Abstract

GLUCOSE (D-glucose) is an essential fuel for the brain and many other tissues. Five glucose-transporter proteins facilitate the diffusion of glucose across lipophilic plasma membranes.1 2 3 This pr...


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