Using zebrafish to model erythroid lineage toxicity and regeneration
Anna Lenard(University Hospital of Basel), Elisa Alghisi(University Hospital of Basel), Hamina Daff(Roche (Switzerland)), Massimiliano Donzelli(Roche (Switzerland)), C. McGinnis(Roche (Switzerland)), Claudia Lengerke(University Hospital of Basel)
Cited by 17Open Access
Abstract
The zebrafish is a vertebrate model organism widely used to study developmental and malignant hematopoiesis. All major mammalian blood cell lineages are present in zebrafish, and many genes and pathways involved in vertebrate hematopoiesis are conserved between fish and mammals.[1][1]–[3][2] The
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