Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Caroline L. Relton; Jie Zheng; John P Kemp; George Davey Smith; David M. Evans; Lavinia Paternoster; Wendy L. McArdle; Jie Zheng; John P Kemp; A. John Henderson; David M Evans; George Davey Smith; Lavinia Paternoster; Elisabeth Thiering; Marie Standl; Carla M. T. Tiesler; Joachim Heinrich; Johannes Waage; Klaus Bønnelykke; Hans Bisgaard; Eskil Kreiner‐Møller; Regina Fölster‐Holst; Melanie Hotze; Elke Rodríguez; Hansjörg Baurecht; Stephan Weidinger; David P. Strachan; Angela Simpson; John A. Curtin; Adnan Ćustović; Joyce Y. Tung; Chao Tian; David A. Hinds; Atsushi Takahashi; Young-Ae Lee; Birgit Kalb; Norbert Hübner; Jorge Esparza-Gordillo; Franz Rüschendorf; Anja Matanovic; Ingo Marenholz; Anja Bauerfeind; Anja Matanovic; Ingo Marenholz; Jorge Esparza-Gordillo; Young-Ae Lee; Alexessander Couto Alves; Jacob P. Thyssen; Liesbeth Duijts; Vincent W. V. Jaddoe; Herman T. den Dekker; Johan C. de Jongste; Albert Hofman; Vincent W V Jaddoe; Liesbeth Duijts; André G Uitterlinden; Fernando Rivadeneira; Herman T den Dekker; Vincent W V Jaddoe; Liesbeth Duijts; Niels J. Elbert; Fernando Rivadeneira; Herman T den Dekker; Manuel A. R. Ferreira; Nicholas G. Martin; Christian Gieger; Elisabeth Altmaier; Elisabeth Altmaier; Christian Gieger; Annette Peters; Elisabeth Altmaier; Janina S. Ried; Christian Gieger; Jin Li; Patrick Sleiman; Hakon Hakonarson; Patrick Sleiman; Hakon Hakonarson; Xian Bo Zuo; Feng Li Xiao; Xian Yin; Xue Jun Zhang; Xiao Zheng; Liang Sun; Jordi Sunyer; Natàlia Vilor-Tejedor; Juan R Gonzalez; Mariona Bustamante; Jordi Sunyer; Natàlia Vilor-Tejedor; Juan R Gonzalez; Mariona Bustamante; Jordi Sunyer; Natàlia Vilor-Tejedor; Juan R Gonzalez; Mariona Bustamante; Susanne Lau; Birgit Kalb; Scott Huntsman; Esteban G. Burchard; Celeste Eng; Maria Pino-Yanes; Donglei Hu; Maria Pino-Yanes; Maria Pino-Yanes; Dirkje S. Postma; Cheng‐Jian Xu; Cheng‐Jian Xu; Lisbeth Carstensen; Mads Melbye; Frank Geller; Bjarke Feenstra; Dorret I. Boomsma; Christel M. Middeldorp; Maria M. Groen‐Blokhuis; Jouke Jan Hottenga; Cristina Venturini; Daniel Glass; Véronique Bataille; Tim D. Spector; Pirro G. Hysi; Craig E. Pennell; Carol A. Wang; Sheila J. Barton; Keith M. Godfrey; Albert M. Levin; Nicole M Probst-Hensch; Ashish Kumar; Ivan Curjuric; Medea Imboden; Nicole M Probst-Hensch; Ashish Kumar; Ivan Curjuric; Medea Imboden; Mariona Bustamante; John W. Holloway; Gabrielle A. Lockett; Jonas Bačelis; Bo Jacobsson; Supinda Bunyavanich; Carole Ober; Rachel A. Myers; Ashish Kumar; Erik Melén; Momoko Horikoshi; Ashish Kumar; Tomomitsu Hirota; Mayumi Tamari; Michiaki Kubo; David M Evans; John P. Kemp; Min Ae Lee‐Kirsch; Andreas Arnold; Georg Homuth; Carsten Oliver Schmidt; Elisabeth Mangold; Markus M Nöthen; Sven Cichon; Markus M Nöthen; Sven Cichon; Sven Cichon; Sven Cichon; Sven Cichon; Thomas Keil; Thomas Keil; Annette Peters; Andre Franke; Wolfgang Lieb; Natalija Novak; Juha Pekkanen; Juha Pekkanen; Sylvain Sebert; Marjo-Riitta Jarvelin; Sylvain Sebert; Marjo-Riitta Jarvelin; Allan Linneberg; Lise Lotte N. Husemoen; Niels Grarup; Fernando Rivadeneira; André G Uitterlinden; Suzanne G.M.A. Pasmans; Niels J. Elbert; Guy B. Marks; Philip J. Thompson; Philip J. Thompson; Melanie C. Matheson; Colin Robertson; Alan D Irvine; Maeve A. McAleer; Alan D Irvine; Maeve A. McAleer; Gráinne M. O’Regan; Alan D Irvine; Caoimhe Fahy; W H Irwin McLean; Linda Campbell; Sara Brown; Milan Macek; Michael Kurek; Carla M. T. Tiesler; Elisabeth Thiering; Badri Pahukasahasram; L. Keoki Williams; James J. Yang; Caroline L. Relton; Wenche Nystad; Ronny Myhre; Bo Jacobsson; Scott T. Weiss; Benjamin A. Raby; Deborah A. Meyers; Cilla Söderhäll; Cilla Söderhäll; Erik Melén; John W. Holloway; Jordi Sunyer; L. Keoki Williams; Keith M. Godfrey; Dorret I. Boomsma; Allan Linneberg; Mads Melbye; Mads Melbye; Gerard H. Koppelman; Deborah Jarvis; Deborah Jarvis; Esteban G. Burchard; Allan Linneberg; Marjo-Riitta Jarvelin; Marjo-Riitta Jarvelin; Sara Brown

doi:10.1038/ng.3424

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

Caroline L. Relton(University of Bristol), Jie Zheng(Helmholtz Zentrum München), John P Kemp(University of Copenhagen), George Davey Smith(University of Bristol), David M. Evans(Translational Research Institute), Lavinia Paternoster(St George's, University of London), Wendy L. McArdle(Manchester Academic Health Science Centre), Jie Zheng(University of Copenhagen), John P Kemp(Translational Research Institute), A. John Henderson(University of Bristol), David M Evans(Translational Research Institute), George Davey Smith(University of Bristol), Lavinia Paternoster(Gentofte Hospital), Elisabeth Thiering(Erasmus MC), Marie Standl(QIMR Berghofer Medical Research Institute), Carla M. T. Tiesler(Helmholtz Zentrum München), Joachim Heinrich(Children's Hospital of Philadelphia), Johannes Waage(University of Copenhagen), Klaus Bønnelykke(University of Copenhagen), Hans Bisgaard(University of Copenhagen), Eskil Kreiner‐Møller(University of Copenhagen), Regina Fölster‐Holst(University of California, San Francisco), Melanie Hotze(University Medical Center Groningen), Elke Rodríguez(Statens Serum Institut), Hansjörg Baurecht(University Hospital Schleswig-Holstein), Stephan Weidinger(King's College London), David P. Strachan(St George's, University of London), Angela Simpson(Manchester Academic Health Science Centre), John A. Curtin(Henry Ford Health System), Adnan Ćustović(Swiss Tropical and Public Health Institute), Joyce Y. Tung(Universitat Pompeu Fabra), Chao Tian(University of Copenhagen), David A. Hinds(23andMe (United States)), Atsushi Takahashi(Sahlgrenska University Hospital), Young-Ae Lee(Max Delbrück Center), Birgit Kalb(Max Delbrück Center), Norbert Hübner(Max Delbrück Center), Jorge Esparza-Gordillo(Centre for Human Genetics), Franz Rüschendorf(Max Delbrück Center), Anja Matanovic(Max Delbrück Center), Ingo Marenholz(Max Delbrück Center), Anja Bauerfeind(Max Delbrück Center), Anja Matanovic (Max Delbrück Center), Ingo Marenholz(Translational Research Institute), Jorge Esparza-Gordillo(Max Delbrück Center), Young-Ae Lee(Max Delbrück Center), Alexessander Couto Alves(Max Delbrück Center), Jacob P. Thyssen(Max Delbrück Center), Liesbeth Duijts(Erasmus MC), Vincent W. V. Jaddoe(Universitätsmedizin Greifswald), Herman T. den Dekker(Erasmus MC), Johan C. de Jongste(Universitätsmedizin Greifswald), Albert Hofman(University of Bonn), Vincent W V Jaddoe(University of Bonn), Liesbeth Duijts(University of Würzburg), André G Uitterlinden (Erasmus MC), Fernando Rivadeneira(Erasmus MC), Herman T den Dekker(Erasmus MC), Vincent W V Jaddoe(Erasmus MC), Liesbeth Duijts(University of Bonn), Niels J. Elbert(Erasmus MC), Fernando Rivadeneira(Centre for Human Genetics), Herman T den Dekker(University of Helsinki), Manuel A. R. Ferreira(QIMR Berghofer Medical Research Institute), Nicholas G. Martin(QIMR Berghofer Medical Research Institute), Christian Gieger(University of Copenhagen), Elisabeth Altmaier (Erasmus MC), Elisabeth Altmaier(Erasmus MC), Christian Gieger(Erasmus MC), Annette Peters(Erasmus MC), Elisabeth Altmaier(Erasmus MC), Janina S. Ried(Erasmus MC), Christian Gieger(Erasmus MC), Jin Li(The University of Sydney), Patrick Sleiman(Children's Hospital of Philadelphia), Hakon Hakonarson(Children's Hospital of Philadelphia), Patrick Sleiman(Children's Hospital of Philadelphia), Hakon Hakonarson(Children's Hospital of Philadelphia), Xian Bo Zuo(Children's Hospital of Philadelphia), Feng Li Xiao(Anhui Medical University), Xian Yin(Anhui Medical University), Xue Jun Zhang(Anhui Medical University), Xiao Zheng(Anhui Medical University), Liang Sun(Anhui Medical University), Jordi Sunyer(Universitat Pompeu Fabra), Natàlia Vilor-Tejedor (Universitat Pompeu Fabra), Juan R Gonzalez(University of Dundee), Mariona Bustamante(Universitat Pompeu Fabra), Jordi Sunyer(Universitat Pompeu Fabra), Natàlia Vilor-Tejedor (Universitat Pompeu Fabra), Juan R Gonzalez(University of California, San Francisco), Mariona Bustamante(University Medical Center Groningen), Jordi Sunyer(Statens Serum Institut), Natàlia Vilor-Tejedor (Statens Serum Institut), Juan R Gonzalez(Center for Research in Environmental Epidemiology), Mariona Bustamante(Universitat Pompeu Fabra), Susanne Lau(King's College London), Birgit Kalb(King's College London), Scott Huntsman(University of California, San Francisco), Esteban G. Burchard(University of California, San Francisco), Celeste Eng(University of California, San Francisco), Maria Pino-Yanes(Henry Ford Health System), Donglei Hu(University of California, San Francisco), Maria Pino-Yanes(Swiss Tropical and Public Health Institute), Maria Pino-Yanes(University of California, San Francisco), Dirkje S. Postma(University Medical Center Groningen), Cheng‐Jian Xu(University Medical Center Groningen), Cheng‐Jian Xu(Norwegian Institute of Public Health), Lisbeth Carstensen(Statens Serum Institut), Mads Melbye(Statens Serum Institut), Frank Geller(Statens Serum Institut), Bjarke Feenstra(Statens Serum Institut), Dorret I. Boomsma(Karolinska Institutet), Christel M. Middeldorp(Karolinska Institutet), Maria M. Groen‐Blokhuis(University of Chicago), Jouke Jan Hottenga(Brigham and Women's Hospital), Cristina Venturini(King's College London), Daniel Glass(Norwegian Institute of Public Health), Véronique Bataille(King's College London), Tim D. Spector(University of Copenhagen), Pirro G. Hysi(Universitat Pompeu Fabra), Craig E. Pennell(Swiss Tropical and Public Health Institute), Carol A. Wang(Henry Ford Health System), Sheila J. Barton(National Health Service), Keith M. Godfrey(National Health Service), Albert M. Levin(Henry Ford Health System), Nicole M Probst-Hensch(Statens Serum Institut), Ashish Kumar(University Medical Center Groningen), Ivan Curjuric(Swiss Tropical and Public Health Institute), Medea Imboden(Swiss Tropical and Public Health Institute), Nicole M Probst-Hensch(Swiss Tropical and Public Health Institute), Ashish Kumar(Centre for Human Genetics), Ivan Curjuric(Children's Hospital of Philadelphia), Medea Imboden(Swiss Tropical and Public Health Institute), Mariona Bustamante(Universitat Pompeu Fabra), John W. Holloway(QIMR Berghofer Medical Research Institute), Gabrielle A. Lockett(Erasmus MC), Jonas Bačelis(University of Copenhagen), Bo Jacobsson(Norwegian Institute of Public Health), Supinda Bunyavanich(University of Bonn), Carole Ober(University of Chicago), Rachel A. Myers(Max Delbrück Center), Ashish Kumar (Centre for Human Genetics), Erik Melén(Karolinska Institutet), Momoko Horikoshi(Centre for Human Genetics), Ashish Kumar (Centre for Human Genetics), Tomomitsu Hirota(University of Dundee), Mayumi Tamari(Helmholtz Zentrum München), Michiaki Kubo(Translational Research Institute), David M Evans(Translational Research Institute), John P. Kemp(Translational Research Institute), Min Ae Lee‐Kirsch(Klinik und Poliklinik für Kinder- und Jugendmedizin), Andreas Arnold(Universitätsmedizin Greifswald), Georg Homuth(Universität Greifswald), Carsten Oliver Schmidt(Universitätsmedizin Greifswald), Elisabeth Mangold(University of Bonn), Markus M Nöthen(University of Bonn), Sven Cichon(University of Bonn), Markus M Nöthen(University of Bonn), Sven Cichon(University of Bonn), Sven Cichon(University of Bonn), Sven Cichon(University of Bonn), Sven Cichon(University of Bonn), Thomas Keil(University of Würzburg), Thomas Keil(University of Würzburg), Annette Peters(Helmholtz Zentrum München), Andre Franke(Christian-Albrechts-Universität zu Kiel), Wolfgang Lieb(Christian-Albrechts-Universität zu Kiel), Natalija Novak(University of Bonn), Juha Pekkanen(University of Helsinki), Juha Pekkanen(University of Helsinki), Sylvain Sebert (University of Oulu), Marjo-Riitta Jarvelin(Oulu University Hospital), Sylvain Sebert (University of Oulu), Marjo-Riitta Jarvelin(Oulu University Hospital), Allan Linneberg(University of Copenhagen), Lise Lotte N. Husemoen(Capital Region of Denmark), Niels Grarup(University of Copenhagen), Fernando Rivadeneira (Erasmus MC), André G Uitterlinden(Erasmus MC), Suzanne G.M.A. Pasmans(Erasmus MC), Niels J. Elbert(Erasmus MC), Guy B. Marks(The University of Sydney), Philip J. Thompson(The University of Western Australia), Philip J. Thompson(The University of Western Australia), Melanie C. Matheson(The University of Melbourne), Colin Robertson(Murdoch Children's Research Institute), Alan D Irvine(Trinity College Dublin), Maeve A. McAleer(Children's Health Ireland at Crumlin), Alan D Irvine(Trinity College Dublin), Maeve A. McAleer(Children's Health Ireland at Crumlin), Gráinne M. O’Regan(Children's Health Ireland at Crumlin), Alan D Irvine(Trinity College Dublin), Caoimhe Fahy(Trinity College Dublin), W H Irwin McLean (University of Dundee), Linda Campbell(University of Dundee), Sara Brown(University of Dundee), Milan Macek(Charles University), Michael Kurek(Pomeranian Medical University), Carla M. T. Tiesler(Helmholtz Zentrum München), Elisabeth Thiering(Helmholtz Zentrum München), Badri Pahukasahasram(Henry Ford Health System), L. Keoki Williams(Henry Ford Health System), James J. Yang(University of Michigan), Caroline L. Relton(University of Bristol), Wenche Nystad(Norwegian Institute of Public Health), Ronny Myhre(Norwegian Institute of Public Health), Bo Jacobsson(Norwegian Institute of Public Health), Scott T. Weiss(Brigham and Women's Hospital), Benjamin A. Raby(Brigham and Women's Hospital), Deborah A. Meyers(Wake Forest University), Cilla Söderhäll(Karolinska Institutet), Cilla Söderhäll(Karolinska Institutet), Erik Melén(Karolinska Institutet), John W. Holloway(University of Southampton), Jordi Sunyer(Universitat Pompeu Fabra), L. Keoki Williams(Henry Ford Health System), Keith M. Godfrey(National Health Service), Dorret I. Boomsma(Amsterdam Public Health), Allan Linneberg(University of Copenhagen), Mads Melbye (Statens Serum Institut), Mads Melbye(Statens Serum Institut), Gerard H. Koppelman(University Medical Center Groningen), Deborah Jarvis(Public Health England), Deborah Jarvis(Public Health England), Esteban G. Burchard(University of California, San Francisco), Allan Linneberg(University of Copenhagen), Marjo-Riitta Jarvelin(Oulu University Hospital), Marjo-Riitta Jarvelin(Oulu University Hospital), Sara Brown(University of Dundee)

Nature Genetics

October 19, 2015

10.1038/ng.3424

Cited by 658Open Access

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