Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling

M. Beeram(The University of Texas Health Science Center at San Antonio), Qing Tan, RR Tekmal(The University of Texas Health Science Center at San Antonio), Douglas Russell, Amanda K. Middleton, Linda A. deGraffenried

Annals of Oncology

August 1, 2007

10.1093/annonc/mdm170

Cited by 170

Abstract

Related Papers

The protein kinase B/Akt signalling pathway in human malignancy

K. M. Nicholson, Neil G. Anderson|Cellular Signalling|2002|1.6k

Phosphatidylinositol 3-Kinase/AKT-mediated Activation of Estrogen Receptor α

Robert A. Campbell, Poornima Bhat‐Nakshatri, Nikhil Patel et al.|Journal of Biological Chemistry|2001|968

Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy

Hans-Guido Wendel, Elisa de Stanchina, Jordan S. Fridman et al.|Nature|2004|947

Akt, a Pleckstrin Homology Domain Containing Kinase, Is Activated Primarily by Phosphorylation

Aimee D. Kohn, Fumito Takeuchi, Richard A. Roth|Journal of Biological Chemistry|1996|474

Activation of AKT/PKB in breast cancer predicts a worse outcome among endocrine treated patients

and members of the Southeast Sweden Breast Cancer Group, Gizeh Pérez‐Tenorio, Olle Stål|British Journal of Cancer|2002|393