Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin
Steven D. Knight(GlaxoSmithKline (United States)), Dashyant Dhanak(Wilmington University), Richard R. Gontarek(South College), David Sutton(South College), Martha A. Sarpong(South College), Juan I. Luengo(South College), Christine Gardiner(South College), P.A. Elkins(South College), S. Gilbert, Carla A. Donatelli(South College), Michael G. Darcy(South College), Eric Garver(South College), Amita M. Chaudhari(South College), Peter J. Tummino(Intarcia Therapeutics (United States)), Christian Sherk(GlaxoSmithKline (United States)), Ronald Wegrzyn(South College), Stanley J. Schmidt(South College), Glenn S. Van Aller(GlaxoSmithKline (United Kingdom)), Kevin L. Kershner(South College), Joelle L. Burgess(GlaxoSmithKline (United States)), Kaushik Raha(RELX Group (Netherlands)), Lusong Luo(Beijing Biocytogen (China)), Jeffrey R. Jackson(New Frontier), K. A. NEWLANDER(South College), Chiu-Mei Sung(South College), Kurt R. Auger(Research Triangle Park Foundation), Melody Diamond(South College), Cynthia A. Parrish(South College), Lance H. Ridgers(South College), Nicholas D. Adams(South College), Jeffrey D. Carson(GlaxoSmithKline (United States))
Cited by 374
Related Papers
Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori
|Nature|1999|1.9k
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
|Nature|2012|1.8k
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
|Nature|2011|1.5k
Hydrolysis of Biological Peptides by Human Angiotensin-converting Enzyme-related Carboxypeptidase
|Journal of Biological Chemistry|2002|1.4k
The promise and peril of chemical probes
|Nature Chemical Biology|2015|848