The Microtubule-Stabilizing Agent Discodermolide Competitively Inhibits the Binding of Paclitaxel (Taxol) to Tubulin Polymers, Enhances Tubulin Nucleation Reactions More Potently than Paclitaxel, and Inhibits the Growth of Paclitaxel-Resistant Cells
Richard Kowalski(National Institutes of Health), Paraskevi Giannakakou(National Cancer Institute), Sarath P. Gunasekera(National Cancer Institute), Ross E. Longley(Harbor Branch Oceanographic Institute), Billy W. Day(Harbor Branch Oceanographic Institute), Ernest Hamel(Harbor Branch Oceanographic Institute)
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