Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

Bing Gong; Yong Pan; Prashant Vempati; Wei Zhao; Lindsay Knable; Lap Ho; Jun Wang; Magdalena Sastre; Kenjiro Ono; Anthony A. Sauve; Giulio Maria Pasinetti

doi:10.1016/j.neurobiolaging.2012.12.005

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

Bing Gong(Icahn School of Medicine at Mount Sinai), Yong Pan(Icahn School of Medicine at Mount Sinai), Prashant Vempati(Icahn School of Medicine at Mount Sinai), Wei Zhao(Icahn School of Medicine at Mount Sinai), Lindsay Knable(Icahn School of Medicine at Mount Sinai), Lap Ho(Icahn School of Medicine at Mount Sinai), Jun Wang(Icahn School of Medicine at Mount Sinai), Magdalena Sastre(Imperial College London), Kenjiro Ono(Icahn School of Medicine at Mount Sinai), Anthony A. Sauve(Cornell University), Giulio Maria Pasinetti(James J. Peters VA Medical Center)

Neurobiology of Aging

January 9, 2013

10.1016/j.neurobiolaging.2012.12.005

Cited by 342Open Access

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