Clustered Pathway Genes in Aflatoxin Biosynthesis

Jiujiang Yu(Agricultural Research Service), Perng‐Kuang Chang(Agricultural Research Service), Kenneth C. Ehrlich(Agricultural Research Service), Jeffrey W. Cary(Agricultural Research Service), Deepak Bhatnagar(Southern Regional Research Center), Thomas E. Cleveland(Agricultural Research Service), Gary A. Payne(North Carolina State University), John E. Linz(Michigan State University), Charles P. Woloshuk(Purdue University West Lafayette), Joan W. Bennett(Tulane University)
Applied and Environmental Microbiology
March 1, 2004
Cited by 793Open Access
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Abstract

Aflatoxins, a group of polyketide-derived furanocoumarins (Fig. [1][1]), are the most toxic and carcinogenic compounds among the known mycotoxins. Among the at least 16 structurally related aflatoxins characterized, however, there are only four major aflatoxins, B1, B2, G1, and G2 (AFB1, AFG1, AFB2


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