Bone regeneration and stem cells
Kristina Arvidson(University of Bergen), Basem M. Abdallah(University of Southern Denmark), Lee Ann Applegate(University Hospital of Lausanne), Nicola Baldini(Istituto Ortopedico Rizzoli), E. Cenni(Istituto Ortopedico Rizzoli), Enrique Gómez‐Barrena(Hospital Universitario La Paz), Donatella Granchi(Istituto Ortopedico Rizzoli), Moustapha Kassem(University of Southern Denmark), Yrjö T. Konttinen(Helsinki University Hospital), Kamal Mustafa(University of Bergen), Dominique P. Pioletti(University Hospital of Lausanne), Tarvo Sillat(Helsinki University Hospital), Anna Finne‐Wistrand(KTH Royal Institute of Technology)
Cited by 400Open Access
Abstract
This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair, osteogenesis and its molecular markers. A variety of cells in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, are discussed.
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