Pain reduction with oral methotrexate in knee osteoarthritis, a pragmatic phase iii trial of treatment effectiveness (PROMOTE): study protocol for a randomized controlled trial
Sarah R. Kingsbury(University of Leeds), Philip G. Conaghan(University of Leeds), Kim Cocks(University of Leeds), Michael Doherty(University of Nottingham), Michael Batley(Maidstone and Tunbridge Wells NHS Trust), Toby Garrood(Guy's and St Thomas' NHS Foundation Trust), Edward Roddy(Midlands Partnership NHS Foundation Trust), Nigel Arden(Nuffield Orthopaedic Centre), David L. Scott(Oregon Health & Science University), Fraser Birrell(Newcastle University), Fiona E. Watt(Imperial College Healthcare NHS Trust), Andrew J. Grainger(Cambridge University Hospitals NHS Foundation Trust), Robert J. Moots(Edge Hill University), Puvan Tharmanathan(University of York), Michael Green(Children's Hospital of Pittsburgh), David Torgerson(University of York), Rod Hughes(AstraZeneca (Singapore)), Catherine Hewitt(University of York), C J Edwards(University of Southampton), Terence W O’Neill(NIHR Oxford Musculoskeletal Biomedical Research Centre)
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