G Protein-Coupled Receptor Kinase 6 Acts as a Critical Regulator of Cytokine-Induced Hyperalgesia by Promoting Phosphatidylinositol 3-Kinase and Inhibiting p38 Signaling

Niels Eijkelkamp(Utrecht University), Annemieke Kavelaars(The University of Texas MD Anderson Cancer Center)
Molecular Medicine
February 6, 2012
10.2119/molmed.2011.00398
Cited by 27

Related Papers

Macrophages transfer mitochondria to sensory neurons to resolve inflammatory pain
|Neuron|2021|240
GRK2: A Novel Cell-Specific Regulator of Severity and Duration of Inflammatory Pain
|Journal of Neuroscience|2010|106
Balancing GRK2 and EPAC1 levels prevents and relieves chronic pain
|Journal of Clinical Investigation|2013|97
CD8+ T cell–derived IL-13 increases macrophage IL-10 to resolve neuropathic pain
|JCI Insight|2022|93
Low Nociceptor GRK2 Prolongs Prostaglandin E<sub>2</sub>Hyperalgesia via Biased cAMP Signaling to Epac/Rap1, Protein Kinase Cε, and MEK/ERK
|Journal of Neuroscience|2010|88