The Blomia tropicalis Allergens
Kaw Yan Chua(National University of Singapore), Nge Cheong, I-Chun Kuo, Bee Wah Lee, Fong Cheng Yi, Chiung‐Hui Huang, Lip Nyin Liew(National University of Singapore)
Cited by 51
Abstract
Blomia tropicalis allergens are the most important mite allergens in tropical regions. Most of them only have 30-40% sequence identity with their Dermatophagoides counterparts and they share low IgE cross reactivity and exhibit different immunobiology. Unlike the pyroglyphid counterparts, Blo t 5 is the major allergen whereas Blo t 1 only has modest allergenicity. Keywords: Dermatophagoides, cysteine protease, house dust mite allergens, IgE, RACE cDNA amplification
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