OATP1A/1B Transporters Affect Irinotecan and SN-38 Pharmacokinetics and Carboxylesterase Expression in Knockout and Humanized Transgenic Mice

Dilek Iusuf(Utrecht University), Alfred H. Schinkel(Oncode Institute), Martin van der Valk, Olaf van Tellingen(Dutch Cancer Society), Ahmed M.O. Elbatsh(Oncode Institute), Anita van Esch, Els Wagenaar(The Netherlands Cancer Institute), Fan Lin(University of Chinese Academy of Sciences), Marion Ludwig(The Netherlands Cancer Institute), Evita van de Steeg(Netherlands Organisation for Applied Scientific Research)
Molecular Cancer Therapeutics
November 5, 2013
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