Regularization Paths for Cox's Proportional Hazards Model via Coordinate Descent

Noah Simon(Stanford University), J. Friedman(Stanford University), Trevor Hastie(Stanford University), Rob Tibshirani(Stanford University)
Journal of Statistical Software
January 1, 2011
Cited by 2,591Open Access
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Abstract

We introduce a pathwise algorithm for the Cox proportional hazards model, regularized by convex combinations of <em>l</em><sub>1</sub> and <em>l</em><sub>2</sub> penalties (elastic net). Our algorithm fits via cyclical coordinate descent, and employs warm starts to find a solution along a regularization path. We demonstrate the efficacy of our algorithm on real and simulated data sets, and find considerable speedup between our algorithm and competing methods.


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