Synthesis of functionalized isoxazole–oxindole hybrids <i>via</i> on water, catalyst free vinylogous Henry and 1,6-Michael addition reactions
Sakkani Nagaraju(National Institute of Technology Warangal), Neeli Satyanarayana(National Institute of Technology Warangal), Banoth Paplal(National Institute of Technology Warangal), Anuji K. Vasu(Indian Institute of Technology Gandhinagar), Sriram Kanvah(Indian Institute of Technology Gandhinagar), Dhurke Kashinath(National Institute of Technology Warangal)
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Abstract
Various isoxazole–oxindole hybrids were synthesized <italic>via</italic> vinylogous Henry reaction of 3,5-dimethyl-4-nitroisoxazole and isatin under catalyst free conditions in water. The products obtained were functionalized using 1,6-Michael addition reaction.
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