On‐Demand Drug Release System for In Vivo Cancer Treatment through Self‐Assembled Magnetic Nanoparticles
Jae‐Hyun Lee(Yonsei University), Kuan‐Ju Chen(Institute for Molecular Medicine), Seung‐Hyun Noh(Yonsei University), Mitch A. Garcia(California NanoSystems Institute), Hao Wang(University of California, Los Angeles), Wei‐Yu Lin(Institute for Molecular Medicine), Heeyeong Jeong(Yonsei University), Brian Junoh Kong(California NanoSystems Institute), David B. Stout(University of California, Los Angeles), Jinwoo Cheon(California NanoSystems Institute), Hsian‐Rong Tseng(Institute for Molecular Medicine)
Cited by 230
Abstract
On-demand drug release: Magnetothermally responsive drug-encapsulated supramolecular nanoparticles for on-demand drug release in vivo have been developed. The remote application of an alternative magnetic field heats the magnetic particles that effectively trigger the release of the drug. An acute drug concentration can be delivered to the tumor in vivo, resulting in an improved therapeutic outcome.
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