Highly Efficient Asymmetric Michael Addition of Aldehydes to Nitroalkenes Catalyzed by a Simple <i>trans</i>‐4‐Hydroxyprolylamide

Abstract

Discriminating reactions: While no self-aldol reaction is observed in the reaction shown, catalyst 1 promotes the Michael addition of aldehydes to nitroalkenes with the lowest catalyst loading and lowest stoichiometric ratio of reactant aldehyde that have been reported so far for this type of reaction. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2006/z602207_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.