Sites for Antagonism on the N-Methyl-D-Aspartate Receptor Channel Complex

Erik H.F. Wong(Merck & Co., Inc., Rahway, NJ, USA (United States)), J A Kemp
The Annual Review of Pharmacology and Toxicology
April 1, 1991
Cited by 219

Abstract

Heme oxygenases (HO) catabolize free heme, that is, iron (Fe) protoporphyrin (IX), into equimolar amounts of Fe2+, carbon monoxide (CO), and biliverdin. The stress-responsive HO-1 isoenzyme affords protection against programmed cell death. The mechanism ...Read More


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