SINGLE-PARTICLE TRACKING:Applications to Membrane Dynamics
Michael J. Saxton(University of California, Davis), Ken Jacobson(University of North Carolina at Chapel Hill)
Cited by 1,825
Abstract
Measurements of trajectories of individual proteins or lipids in the plasma membrane of cells show a variety of types of motion. Brownian motion is observed, but many of the particles undergo non-Brownian motion, including directed motion, confined motion, and anomalous diffusion. The variety of motion leads to significant effects on the kinetics of reactions among membrane-bound species and requires a revision of existing views of membrane structure and dynamics.
Related Papers
Interactions between saturated acyl chains confer detergent resistance on lipids and glycosylphosphatidylinositol (GPI)-anchored proteins: GPI-anchored proteins in liposomes and cells show similar behavior.
Rolf Schroeder, Erwin London, Douglas Brown|Proceedings of the National Academy of Sciences|1994|686