Cavitary Disease and Quantitative Sputum Bacillary Load in Cases of Pulmonary Tuberculosis
Moisés Palaci(Universidade Federal do Espírito Santo), Reynaldo Dietze(Universidade Federal do Espírito Santo), David Jamil Hadad(Universidade Federal do Espírito Santo), Fabíola Karla Ribeiro(Universidade Federal do Espírito Santo), Renata Lyrio Peres(Universidade Federal do Espírito Santo), Solange Alves Vinhas(Universidade Federal do Espírito Santo), Ethel Leonor Nóia Maciel(Universidade Federal do Espírito Santo), Valdério do Valle Dettoni(Universidade Federal do Espírito Santo), Libby Horter(University Hospitals Cleveland Medical Center), W. Henry Boom(University Hospitals Cleveland Medical Center), John L. Johnson(University Hospitals Cleveland Medical Center), Kathleen D. Eisenach(University of Arkansas for Medical Sciences)
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Abstract
We examined sputum bacterial loads in adults with newly diagnosed tuberculosis using quantitative culture and time-until-positive (DTP) culture in BACTEC 460. Patients with cavitary disease had higher CFU levels than those without cavities and shorter DTPs. Within radiographic strata of moderately and far advanced tuberculosis, higher CFU counts were associated with cavitary disease.
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