Global implementation of genomic medicine: We are not alone

Teri A. Manolio(National Human Genome Research Institute), Marc Abramowicz(Université Libre de Bruxelles), Fahd Al‐Mulla(Kuwait University), Warwick P. Anderson(National Health and Medical Research Council), Rudi Balling(University of Luxembourg), Adam C. Berger(State Board of Education), Steven B. Bleyl(Intermountain Healthcare), Aravinda Chakravarti(Johns Hopkins University), Wasun Chantratita(Ramathibodi Hospital), Rex L. Chisholm(Northwestern University), Vajira H. W. Dissanayake(University of Colombo), Michael Dunn(Wellcome Trust Centre for the History of Medicine), Victor J. Dzau(National Academy of Medicine), Bok‐Ghee Han(Korea National Institute of Health), Tim Hubbard(Genomics England), Anne Kolbe(Auckland District Health Board), Bruce R. Korf(University of Alabama at Birmingham), Michiaki Kubo(RIKEN Center for Integrative Medical Sciences), Paul Lasko(Canadian Institutes of Health Research), Erkki Leego(Estonian Biocentre), Surakameth Mahasirimongkol(Ministry of Public Health), Partha P. Majumdar(National Institute of Biomedical Genomics), Gert Matthijs(Center for Human Genetics), Howard L. McLeod(Moffitt Cancer Center), Andres Metspalu(Estonian Biocentre), Pierre Meulien(Genome Canada), Satoru Miyano(Tokyo Medical University), Yaakov Naparstek(Hebrew University of Jerusalem), P. Pearl O’Rourke(Mass General Brigham), George P. Patrinos(University of Patras), Heidi L. Rehm(Mass General Brigham), Mary V. Relling(St. Jude Children's Research Hospital), Gad Rennert(Carmel Medical Center), Laura Lyman Rodriguez(National Human Genome Research Institute), Dan M. Roden(Vanderbilt University), Alan R. Shuldiner(University of Maryland, Baltimore), Sukdeb Sinha(Ministry of Science and Technology), Patrick Tan(National University of Singapore), Mats Ulfendahl(Swedish Research Council), Robyn L. Ward(The University of Queensland), Marc S. Williams(Geisinger Health System), John E.L. Wong(National University of Singapore), Eric D. Green(National Human Genome Research Institute), Geoffrey S. Ginsburg(Duke University)
Science Translational Medicine
June 3, 2015
Cited by 244Open Access
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Abstract

Around the world, innovative genomic-medicine programs capitalize on singular capabilities arising from local health care systems, cultural or political milieus, and unusual selected risk alleles or disease burdens. Such individual efforts might benefit from the sharing of approaches and lessons learned in other locales. The U.S. National Human Genome Research Institute and the National Academy of Medicine recently brought together 25 of these groups to compare projects, to examine the current state of implementation and desired near-term capabilities, and to identify opportunities for collaboration that promote the responsible practice of genomic medicine. Efforts to coalesce these groups around concrete but compelling signature projects should accelerate the responsible implementation of genomic medicine in efforts to improve clinical care worldwide.


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