A High‐Yielding Biocatalytic Process for the Production of 2‐<i>O</i>‐(α‐<scp>D</scp>‐glucopyranosyl)‐<i>sn</i>‐glycerol, a Natural Osmolyte and Useful Moisturizing Ingredient
Christiane Goedl(Graz University of Technology), Thornthan Sawangwan(Graz University of Technology), Mario Mueller(Graz University of Technology), Alexandra Schwarz(Graz University of Technology), Bernd Nidetzky(Graz University of Technology)
Cited by 127
Abstract
Fit for industry: Stereochemically pure 2-O-(α-D-glucopyranosyl)-sn-glycerol (αGG) was obtained in high yield from an efficient and selective biocatalytic process (see schematic outline). The sucrose phosphorylase catalyzed transfer of a glucosyl group from sucrose to glycerol unites the main advantages of transglycosidases, glycosyltransferases, and glycosynthases for glycoside synthesis and provides access to αGG as an industrial chemical.
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