Anatomic Versus Physiologic Assessment of Coronary Artery Disease
K. Lance Gould(The University of Texas Health Science Center at Houston), Nils P. Johnson(The University of Texas Health Science Center at Houston), Timothy M. Bateman(University of Missouri–Kansas City), Rob Beanlands(University of Ottawa), Frank M. Bengel(Medizinische Hochschule Hannover), Robert Bober(Ochsner Medical Center), Paolo G. Camici(Vita-Salute San Raffaele University), Manuel D. Cerqueira(Cleveland Clinic), Benjamin J.W. Chow(University of Ottawa), Marcelo F. Di Carli(Harvard University Press), Sharmila Dorbala(Brigham and Women's Hospital), Henry Gewirtz(Harvard University Press), Robert J. Gropler(Mallinckrodt (United States)), Philipp A. Kaufmann(University of Zurich), Paul Knaapen(Amsterdam UMC Location VUmc), Juhani Knuuti(Turku PET Centre), Michael E. Merhige, K.Peter Rentrop, Terrence D. Ruddy(University of Ottawa), Heinrich R. Schelbert(University of California, Los Angeles), Thomas H. Schindler(University Hospital of Geneva), Markus Schwaiger, Stefano Sdringola(The University of Texas Health Science Center at Houston), John Vitarello, Kim A. Williams(Wayne State University), Donald Gordon(Cardiovascular Research Associates), Vasken Dilsizian(University of Maryland, Baltimore), Jagat Narula(Cardiovascular Institute of the South)
Cited by 562Open Access
Abstract
Angiographic severity of coronary artery stenosis has historically been the primary guide to revascularization or medical management of coronary artery disease. However, physiologic severity defined by coronary pressure and/or flow has resurged into clinical prominence as a potential, fundamental change from anatomically to physiologically guided management. This review addresses clinical coronary physiology-pressure and flow-as clinical tools for treating patients. We clarify the basic concepts that hold true for whatever technology measures coronary physiology directly and reliably, here focusing on positron emission tomography and its interplay with intracoronary measurements.
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