Nitric oxide and the proliferation of vascular smooth muscle cells

Abstract

with thiol groups to produce nitrosothiols Hence, the effects of NO and the pathophysiological influences on it Vascular smooth muscle cell (VSMC) proliferation is an may also be mediated indirectly, potentiated or inhibited important component of vessel wall remodelling in re-through the availability of these oxygen species. Irresponse to injury, for example, after angioplasty or vein spective of the physiological role of NO in VSMC prolifergrafting, and during atherosclerosis formation. Endo-ation, a pharmacological effect of NO may still be thelium-derived nitric oxide (NO) production is both a exploited to reduce neointima formation and prevent tonic and an induced regulator of blood vessel tone