Incidence of schizophrenia and other psychoses in ethnic minority groups: results from the MRC AESOP Study

Paul Fearon(King's College London), James B. Kirkbride(University of Cambridge), Craig Morgan(King's College London), Paola Dazzan(King's College London), Kevin Morgan(King's College London), Tuhina Lloyd(University of Nottingham), Gerard Hutchinson(University of the West Indies), Jane Tarrant(University of Nottingham), Wai Lun Alan Fung(University of Cambridge), J. Douglas Holloway(University of Bristol), R. Mallett(King's College London), Glynn Harrison(University of Bristol), Julian Leff(King's College London), Peter B. Jones(University of Cambridge), Robin Murray(King's College London)
Psychological Medicine
August 29, 2006
Cited by 540

Abstract

BACKGROUND: The incidence of schizophrenia in the African-Caribbean population in England is reported to be raised. We sought to clarify whether (a) the rates of other psychotic disorders are increased, (b) whether psychosis is increased in other ethnic minority groups, and (c) whether particular age or gender groups are especially at risk. METHOD: We identified all people (n=568) aged 16-64 years presenting to secondary services with their first psychotic symptoms in three well-defined English areas (over a 2-year period in Southeast London and Nottingham and a 9-month period in Bristol). Standardized incidence rates and incidence rate ratios (IRR) for all major psychosis syndromes for all main ethnic groups were calculated. RESULTS: We found remarkably high IRRs for both schizophrenia and manic psychosis in both African-Caribbeans (schizophrenia 9.1, manic psychosis 8.0) and Black Africans (schizophrenia 5.8, manic psychosis 6.2) in men and women. IRRs in other ethnic minority groups were modestly increased as were rates for depressive psychosis and other psychoses in all minority groups. These raised rates were evident in all age groups in our study. CONCLUSIONS: Ethnic minority groups are at increased risk for all psychotic illnesses but African-Caribbeans and Black Africans appear to be at especially high risk for both schizophrenia and mania. These findings suggest that (a) either additional risk factors are operating in African-Caribbeans and Black Africans or that these factors are particularly prevalent in these groups, and that (b) such factors increase risk for schizophrenia and mania in these groups.


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