Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming

Yawei Gao; Jiayu Chen; Ke Li; Tong Wu; Bo Huang; Wenqiang Liu; Xiaochen Kou; Yu Zhang; Hua Huang; Yonghua Jiang; Chao Yao; Xiaolei Liu; Zhiwei Lü; Zijian Xu; Lan Kang; Jun Chen; Hailin Wang; Tao Cai; Shaorong Gao

doi:10.1016/j.stem.2013.02.005

Replacement of Oct4 by Tet1 during iPSC Induction Reveals an Important Role of DNA Methylation and Hydroxymethylation in Reprogramming

Yawei Gao(Chinese Academy of Medical Sciences & Peking Union Medical College), Jiayu Chen(Chinese Academy of Medical Sciences & Peking Union Medical College), Ke Li(National Institute of Biological Sciences, Beijing), Tong Wu(National Institute of Biological Sciences, Beijing), Bo Huang(National Institute of Biological Sciences, Beijing), Wenqiang Liu(National Institute of Biological Sciences, Beijing), Xiaochen Kou(National Institute of Biological Sciences, Beijing), Yu Zhang(National Institute of Biological Sciences, Beijing), Hua Huang(Research Center for Eco-Environmental Sciences), Yonghua Jiang(National Institute of Biological Sciences, Beijing), Chao Yao(National Institute of Biological Sciences, Beijing), Xiaolei Liu(National Institute of Biological Sciences, Beijing), Zhiwei Lü(National Institute of Biological Sciences, Beijing), Zijian Xu(National Institute of Biological Sciences, Beijing), Lan Kang(National Institute of Biological Sciences, Beijing), Jun Chen(National Institute of Biological Sciences, Beijing), Hailin Wang(Research Center for Eco-Environmental Sciences), Tao Cai(National Institute of Biological Sciences, Beijing), Shaorong Gao(Chinese Academy of Medical Sciences & Peking Union Medical College)

Cell stem cell

March 14, 2013

10.1016/j.stem.2013.02.005

Cited by 364Open Access

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