Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells
Simon A. Hawley(University of Dundee), D. Grahame Hardie(University of Dundee)
Cited by 206
Related Papers
Complexes between the LKB1 tumor suppressor, STRADα/β and MO25α/β are upstream kinases in the AMP-activated protein kinase cascade
|Journal of Biology|2003|1.6k
A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis
|Biochemical Journal|2008|76
Mechanisms of Paradoxical Activation of AMPK by the Kinase Inhibitors SU6656 and Sorafenib
|Cell chemical biology|2017|69
BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation
|International Journal of Molecular Sciences|2023|24
AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand
|Biochemical Journal|2024|16