<u>T</u>argeting<u>I</u>nduced<u>L</u>ocal<u>L</u>esions<u>IN</u> <u>G</u>enomes (TILLING) for Plant Functional Genomics

Claire M. McCallum(Fred Hutch Cancer Center), Luca Comai(University of Washington), Elizabeth A. Greene(Fred Hutch Cancer Center), Steven Henikoff(Fred Hutch Cancer Center)
PLANT PHYSIOLOGY
June 1, 2000
10.1104/pp.123.2.439
Cited by 867Open Access
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Abstract

One of the most important breakthroughs in the history of genetics was the discovery that mutations can be induced ([Muller, 1930][1]; [Stadler, 1932][2]). The high frequency with which ionizing radiation and certain chemicals can cause genes to mutate made it possible to perform genetic studies

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