<i>Phytophthora</i> Genome Sequences Uncover Evolutionary Origins and Mechanisms of Pathogenesis

Brett M. Tyler(Lawrence Berkeley National Laboratory), Sucheta Tripathy(Lawrence Berkeley National Laboratory), Xuemin Zhang(Lawrence Berkeley National Laboratory), Paramvir Dehal(Lawrence Berkeley National Laboratory), Rays H. Y. Jiang(Lawrence Berkeley National Laboratory), Andrea Aerts(Lawrence Berkeley National Laboratory), Felipe D. Arredondo(Lawrence Berkeley National Laboratory), Laura Baxter(Lawrence Berkeley National Laboratory), Douda Bensasson(Lawrence Berkeley National Laboratory), Jim Beynon(Lawrence Berkeley National Laboratory), Jarrod Chapman(Lawrence Berkeley National Laboratory), C. M. B. Damasceno(Lawrence Berkeley National Laboratory), Anne E. Dorrance(Lawrence Berkeley National Laboratory), Daolong Dou(Lawrence Berkeley National Laboratory), Allan W. Dickerman(Lawrence Berkeley National Laboratory), Inna Dubchak(Lawrence Berkeley National Laboratory), Matteo Garbelotto(Lawrence Berkeley National Laboratory), Mark Gijzen(Agriculture and Agri-Food Canada), Stuart G. Gordon(Lawrence Berkeley National Laboratory), Francine Govers(Lawrence Berkeley National Laboratory), Niklaus J. Grünwald(Lawrence Berkeley National Laboratory), Wayne Huang(Lawrence Livermore National Laboratory), Kelly Ivors(North Carolina State University), Richard W. Jones(Lawrence Berkeley National Laboratory), Sophien Kamoun(Lawrence Berkeley National Laboratory), Konstantinos Krampis(Lawrence Berkeley National Laboratory), Kurt Lamour(Lawrence Berkeley National Laboratory), Mi‐Kyung Lee(Lawrence Berkeley National Laboratory), W. Hayes McDonald(Lawrence Berkeley National Laboratory), Mónica Medina(Lawrence Berkeley National Laboratory), H.J.G. Meijer(Lawrence Berkeley National Laboratory), Eric K. Nordberg(Lawrence Berkeley National Laboratory), D. J. Maclean(Lawrence Berkeley National Laboratory), Manuel D. Ospina-Giraldo(Lawrence Berkeley National Laboratory), Paul F. Morris(Lawrence Berkeley National Laboratory), Vipaporn Phuntumart(Lawrence Berkeley National Laboratory), Nicholas H. Putnam(Lawrence Berkeley National Laboratory), Sam Rash(Lawrence Berkeley National Laboratory), Jocelyn K. C. Rose(Lawrence Berkeley National Laboratory), Yasuko Sakihama(Lawrence Berkeley National Laboratory), Asaf Salamov(Lawrence Berkeley National Laboratory), Alon Savidor(Lawrence Berkeley National Laboratory), Chantel F. Scheuring(Lawrence Berkeley National Laboratory), Brian M. Smith(Lawrence Berkeley National Laboratory), Bruno Sobral(Lawrence Berkeley National Laboratory), Astrid Terry(Lawrence Berkeley National Laboratory), Trudy Torto-Alalibo(Lawrence Berkeley National Laboratory), Joe Win(Lawrence Berkeley National Laboratory), Zhanyou Xu(Lawrence Berkeley National Laboratory), Hong‐Bin Zhang(Lawrence Berkeley National Laboratory), Igor V. Grigoriev(Lawrence Berkeley National Laboratory), Daniel S. Rokhsar(Lawrence Berkeley National Laboratory), Jeffrey L. Boore(Lawrence Berkeley National Laboratory)
Science
August 31, 2006
10.1126/science.1128796
Cited by 1,079Open Access
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Abstract

Draft genome sequences have been determined for the soybean pathogen Phytophthora sojae and the sudden oak death pathogen Phytophthora ramorum. Oömycetes such as these Phytophthora species share the kingdom Stramenopila with photosynthetic algae such as diatoms, and the presence of many Phytophthora genes of probable phototroph origin supports a photosynthetic ancestry for the stramenopiles. Comparison of the two species' genomes reveals a rapid expansion and diversification of many protein families associated with plant infection such as hydrolases, ABC transporters, protein toxins, proteinase inhibitors, and, in particular, a superfamily of 700 proteins with similarity to known oömycete avirulence genes.

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