Farnesyltransferase Inhibitor FTI-277 Reduces Mortality of Septic Mice along with Improved Bacterial Clearance

Wen Yang(McGill University), Masao Kaneki(Shriners Hospitals for Children - Boston)

Journal of Pharmacology and Experimental Therapeutics

August 27, 2011

10.1124/jpet.111.183558

Cited by 26

Related Papers

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

|PLoS Biology|2010|634

iNOS as a Driver of Inflammation and Apoptosis in Mouse Skeletal Muscle after Burn Injury: Possible Involvement of Sirt1 S-Nitrosylation-Mediated Acetylation of p65 NF-κB and p53

|PLoS ONE|2017|115

Liver-specific Inducible Nitric-oxide Synthase Expression Is Sufficient to Cause Hepatic Insulin Resistance and Mild Hyperglycemia in Mice

|Journal of Biological Chemistry|2011|78

Coenzyme Q10 protects against burn‐induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle

|FEBS Open Bio|2018|42

Burn-induced muscle metabolic derangements and mitochondrial dysfunction are associated with activation of HIF-1α and mTORC1: Role of protein farnesylation

|Scientific Reports|2017|30