Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung; Franz Bauernfeind; Annett Halle; Eivind Ottersen Samstad; Hajime Kono; Kenneth L. Rock; Katherine A. Fitzgerald; Eicke Latz

doi:10.1038/ni.1631

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

Veit Hornung(University of Massachusetts Chan Medical School), Franz Bauernfeind(Ludwig-Maximilians-Universität München), Annett Halle(University of Massachusetts Chan Medical School), Eivind Ottersen Samstad(Norwegian University of Science and Technology), Hajime Kono(University of Massachusetts Chan Medical School), Kenneth L. Rock(University of Massachusetts Chan Medical School), Katherine A. Fitzgerald(University of Massachusetts Chan Medical School), Eicke Latz(University of Massachusetts Chan Medical School)

Nature Immunology

July 6, 2008

10.1038/ni.1631

Cited by 3,009Open Access

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