Impairment of BRCA1-Related DNA Double-Strand Break Repair Leads to Ovarian Aging in Mice and Humans

Shiny Titus(New York Medical College), Fang Li(New York Medical College), Robert Stobezki(New York Medical College), Komala Akula(New York Medical College), Evrim Ünsal(Istanbul Bilim University), Kyungah Jeong(New York Medical College), Maura N. Dickler(Memorial Sloan Kettering Cancer Center), Mark E. Robson(Memorial Sloan Kettering Cancer Center), Fred Moy(New York Medical College), Sumanta Goswami(New York Medical College), Kutluk Oktay(New York Medical College)
Science Translational Medicine
February 13, 2013
Cited by 511

Abstract

DNA double-strand break repair has a central role in oocyte aging.


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