Effect on mood of subthalamic DBS for Parkinson’s disease A consecutive series of 24 patients
Alexandre Berney(University of Bern), Fjg. Vingerhoets(University of Bern), Andrew J. Perrin(University of Bern), Patrice Guex(University of Bern), J.-G. Villemure(University of Bern), P. R. Burkhard(University of Bern), Chawki Benkelfat(University of Bern), Joseph Ghika(University of Bern)
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Abstract
A series of 24 consecutive PD patients were prospectively studied prior to and within 6 months postoperatively for mood, motor, and cognitive status to investigate the effects on mood of subthalamic deep brain stimulation (DBS) in PD. In six patients (25%), mood state worsened significantly, and three were transiently suicidal despite clear motor improvement. Caregivers and patients should be educated about the potential impact of this neurosurgical procedure on mood.
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