Blood Purification Using Functionalized Core/Shell Nanomagnets
Inge K. Herrmann(ETH Zurich), Martin Urner(Swiss Integrative Center for Human Health), Fabian M. Koehler(ETH Zurich), Melanie Hasler(University Hospital of Zurich), Birgit Roth‐Z'graggen(University of Zurich), Robert N. Grass(ETH Zurich), Urs Ziegler(University of Zurich), Beatrice Beck‐Schimmer(University Hospital of Zurich), Wendelin J. Stark(ETH Zurich)
Cited by 129
Abstract
Injection of functional nanomagnets in human blood enables selective removal of disease-causing metals, overdosed drugs, and proteins at the (sub-)nanomolar level. This direct in vivo extraction provides a powerful alternative to classical pharmaceutical treatments as disease-causing agents are removed from the organism rather than treating symptoms from exposure. A number of clinically relevant assays demonstrate blood compatibility of the functional nanomagnets.
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