Adaptation to mTOR kinase inhibitors by amplification of eIF4E to maintain cap-dependent translation
Claire L. Cope(Babraham Institute), Simon J. Cook(Babraham Institute)
Cited by 78
Related Papers
RapV12 antagonizes Ras‐dependent activation of ERK1 and ERK2 by LPA and EGF in Rat‐1 fibroblasts.
|The EMBO Journal|1993|352
Extracellular Signal-regulated Kinases 1/2 Are Serum-stimulated “BimEL Kinases” That Bind to the BH3-only Protein BimEL Causing Its Phosphorylation and Turnover
|Journal of Biological Chemistry|2004|187
ERK1/2‐dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl‐1 and Bcl‐xL
|The EMBO Journal|2007|174
Targeting melanoma’s MCL1 bias unleashes the apoptotic potential of BRAF and ERK1/2 pathway inhibitors
|Nature Communications|2019|73