The A4 Study: Stopping AD Before Symptoms Begin?

Reisa A. Sperling(Brigham and Women's Hospital), Dorene M. Rentz(Brigham and Women's Hospital), Keith A. Johnson(Brigham and Women's Hospital), Jason Karlawish(University of Pennsylvania), Michael Donohue(Alzheimer’s Disease Neuroimaging Initiative), David P. Salmon(Alzheimer’s Disease Neuroimaging Initiative), Paul Aisen(Alzheimer’s Disease Neuroimaging Initiative)
Science Translational Medicine
March 19, 2014
Cited by 770Open Access
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Abstract

A new secondary prevention trial in older people with amyloid accumulation at high risk for Alzheimer's disease dementia should provide insights into whether anti-amyloid therapy can delay cognitive decline.


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