Multifunctionalized Sequence‐Defined Oligomers from a Single Building Block

Pieter Espeel(Ghent University), Lieselot L. G. Carrette(Ghent University), Katarzyna Bury(Ghent University), Sven Capenberghs(Ghent University), José C. Martins(Ghent University), Filip Du Prez(Ghent University), Annemieke Madder(Ghent University)
Angewandte Chemie International Edition
October 31, 2013
Cited by 213

Abstract

Another link in the chain: A thiolactone-based approach for the preparation of multifunctionalized sequence-defined oligomeric structures on solid support was established. The iterative aminolysis/chain extension method with a single building block and a variety of commercial amines allowed for the protecting group free synthesis of various oligomeric motifs with a unique backbone and a preprogrammed organization of side chain functionalities. As a service to our authors and readers, this journal provides supporting information supplied by the authors. Such materials are peer reviewed and may be re-organized for online delivery, but are not copy-edited or typeset. Technical support issues arising from supporting information (other than missing files) should be addressed to the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.


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