InterPro in 2011: new developments in the family and domain prediction database

Sarah Hunter(Université Claude Bernard Lyon 1), P. Jones(Université Claude Bernard Lyon 1), Alex Mitchell(Université Claude Bernard Lyon 1), Rolf Apweiler(Université Claude Bernard Lyon 1), Teresa K. Attwood(Université Claude Bernard Lyon 1), Alex Bateman(Université Claude Bernard Lyon 1), Thomas Bernard(Université Claude Bernard Lyon 1), David Binns(Université Claude Bernard Lyon 1), Peer Bork(Université Claude Bernard Lyon 1), Sarah Burge(Université Claude Bernard Lyon 1), Edouard de Castro(Université Claude Bernard Lyon 1), P. Coggill(Université Claude Bernard Lyon 1), M. Corbett(Université Claude Bernard Lyon 1), Ujjwal Das(Université Claude Bernard Lyon 1), Louise C. Daugherty(Université Claude Bernard Lyon 1), L. Duquenne(Université Claude Bernard Lyon 1), ROBERT FINN(Université Claude Bernard Lyon 1), Matthew Fraser(Université Claude Bernard Lyon 1), Julian Gough(Université Claude Bernard Lyon 1), Daniel H. Haft(Université Claude Bernard Lyon 1), Nicolas Hulo(Université Claude Bernard Lyon 1), Daniel Kahn(Université Claude Bernard Lyon 1), Elizabeth A. Kelly(Université Claude Bernard Lyon 1), Ivica Letunić(Université Claude Bernard Lyon 1), D. Lonsdale(Université Claude Bernard Lyon 1), Rodrigo López(Université Claude Bernard Lyon 1), Mary Madera(Université Claude Bernard Lyon 1), J. Maslen(Université Claude Bernard Lyon 1), C. McAnulla(Université Claude Bernard Lyon 1), J. McDowall(Université Claude Bernard Lyon 1), C. McMenamin(Université Claude Bernard Lyon 1), Huaiyu Mi(Université Claude Bernard Lyon 1), P. Mutowo-Muellenet(Université Claude Bernard Lyon 1), Nicola Mulder(Université Claude Bernard Lyon 1), Darren A. Natale(Université Claude Bernard Lyon 1), Christine Orengo(Université Claude Bernard Lyon 1), Sebastien Pesseat(Université Claude Bernard Lyon 1), Marco Punta(Université Claude Bernard Lyon 1), A. F. Quinn(Université Claude Bernard Lyon 1), Catherine Rivoire(Université Claude Bernard Lyon 1), Amaia Sangrador‐Vegas(Université Claude Bernard Lyon 1), Jeremy Selengut(Université Claude Bernard Lyon 1), Christian J A Sigrist(Université Claude Bernard Lyon 1), Maxim Scheremetjew(Université Claude Bernard Lyon 1), John Tate(Université Claude Bernard Lyon 1), M. Thimmajanarthanan(Université Claude Bernard Lyon 1), Paul D. Thomas(Université Claude Bernard Lyon 1), Cathy Wu(Université Claude Bernard Lyon 1), C. Yeats(Université Claude Bernard Lyon 1), Siew-Yit Yong(Université Claude Bernard Lyon 1)
Nucleic Acids Research
November 16, 2011
10.1093/nar/gkr948
Cited by 1,044Open Access
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Abstract

InterPro (http://www.ebi.ac.uk/interpro/) is a database that integrates diverse information about protein families, domains and functional sites, and makes it freely available to the public via Web-based interfaces and services. Central to the database are diagnostic models, known as signatures, against which protein sequences can be searched to determine their potential function. InterPro has utility in the large-scale analysis of whole genomes and meta-genomes, as well as in characterizing individual protein sequences. Herein we give an overview of new developments in the database and its associated software since 2009, including updates to database content, curation processes and Web and programmatic interfaces.

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